Forensic Science International: Genetics Supplement Series
Volume 3, Issue 1 , Pages e1-e2 , December 2011

DIP–STR: A new marker for resolving unbalanced DNA mixtures

  • D. Hall

      Affiliations

    • Corresponding Author InformationCorresponding author. Tel.: +41 21 314 70 69; fax: +41 21 314 70 90.
  • ,
  • V. Castella

Received 23 August 2011 ,Accepted 23 August 2011.

  • Image Result

    (A) A DIP–STR marker is composed of a DIP polymorphism (S/L alleles) linked to an STR polymorphism (e.g., 3/4 repeats). Arrows indicate PCR primers. (B) DIP–STR results of the mixed stain A, 1μl dilut

    (A) A DIP–STR marker is composed of a DIP polymorphism (S/L alleles) linked to an STR polymorphism (e.g., 3/4 repeats). Arrows indicate PCR primers. (B) DIP–STR results of the mixed stain A, 1μl diluted 1/20 DNA was amplified with S-DIP and STR primers (left panel) and 2μl of DNA with L-DIP and STR primers (right panel). This last shows the positive amplification of the minor DNA component of the mixture which matches one of the suspects.

PII: S1875-1768(11)00066-7

doi: 10.1016/j.fsigss.2011.08.065

Forensic Science International: Genetics Supplement Series
Volume 3, Issue 1 , Pages e1-e2 , December 2011