Genetic polymorphisms of eight X-STR loci of Mentype Argus X-8 kit in Koreans

Yoo, Seong Yeon; Cho, Nam Soo; Park, Sun Wha; Hwang, Jung Hee; Kim, Je Nyun; Chung, Ki Wha; Han, Myun Soo

doi:10.1016/j.fsigss.2011.08.016

« Previous Next »Forensic Science International: Genetics Supplement Series
Volume 3, Issue 1 , Pages e33-e34, December 2011

Genetic polymorphisms of eight X-STR loci of Mentype Argus X-8 kit in Koreans

Seong Yeon Yoo
- Forensic DNA Center, National Forensic Service, Seoul, South Korea
- Department of Biological Science and Research Center for Biotechnology, Kongju National University, Gongju, South Korea
Nam Soo Cho
- Department of Forensic Medicine, Central District Office, National Forensic Service, Daejeon, South Korea
Sun Wha Park
- Department of Biological Science and Research Center for Biotechnology, Kongju National University, Gongju, South Korea
Jung Hee Hwang
- Forensic DNA Center, National Forensic Service, Seoul, South Korea
Je Nyun Kim
- Department of Biological Science and Research Center for Biotechnology, Kongju National University, Gongju, South Korea
Ki Wha Chung
- Department of Biological Science and Research Center for Biotechnology, Kongju National University, Gongju, South Korea
Myun Soo Han
- Forensic DNA Center, National Forensic Service, Seoul, South Korea
- Corresponding author. Tel.: +82 10 4121 7721; fax: +82 2 2600 4866.

Received 4 August 2011; received in revised form 18 August 2011; accepted 22 August 2011. published online 31 October 2011.

Abstract

We have examined 45 Korean haplotype transfers in 41 families at eight X-linked STRs (DXS10135 and DXS8378 in linkage group 1, DXS7132 and DXS10074 in linkage group 2, HPRTB and DXS10101 in linkage group 3, DXS10134 and DXS7423 in linkage group 4) of Mentype Argus X-8 kit. The allele frequencies and haplotype frequencies within the four linkage groups were determined for females and males, respectively. Deviation from Hardy-Weinberg expectation could not be detected (p<0.05). No recombination was observed within each 4 linkage groups, however, six cases of mutation were founded in DXS10135, DXS10101, and DXS10134. Details of X-STR haplotype study in Koreans would be useful in kinship testing and forensic applications.